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Composition: Each gram of the cream contains:
& & Lidocaine 25 mg (2.5%) + Prilocaine 25 mg (2.5%).
* Indications: Ezanal is a topical anaesthetic to be used on normal intact skin to provide dermal analgesia before procedures
& & requiring i.v. cannulation, venipuncture, surgical treatment of localized lesions or split skin grafting. Ezanal cream is also effective
& & in providing pain relief during laser treatment.
* Dosage and method of administration:
& & Apply a thick layer of the cream to intact skin and cover with an occlusive dressing. Dermal analgesia will increase for up to
& & 2 hours under occlusive dressing and persist for 1-2 hours after removal of the cream.
& & – Adults:
& & # Minor dermal procedures (e.g. Venipuncture or intravenous cannulation): apply 2.5gm of the cream over skin surface of 20-25cm
& & for not less than one hour.
& & # Major dermal procedures (more painful involving larger skin area such as split thickness, skin graft harvesting): apply 2gm
& & of the cream per 10 Cm2 of skin surface for a contact time of not less than 2 hours.
& & # Adult male genital skin: as an adjunct prior to local anaesthetic infiltration. Apply a thick layer of the cream (1gm/10Cm2) of skin
& & surface for 15 minutes. Local anaesthetic infiltration should be performed immediately after removal of the cream.
& & – Pediatric patients:
& & The following data shows the recommended maximum dose of Ezanal cream / maximum application area and application time
& & by age and body weight for infants and children:
& & < 3 months or < 5Kg ............. 1gm Ezanal / 10 Cm2 / 1 hour.
& & 3-12 months and > 5Kg………….. 2gm Ezanal / 20 Cm2 / 4 hour.
& & 1-6 years and > 10Kg………….10gm Ezanal / 100 Cm2 / 4 hour.
& & 7-12 years and > 20Kg………….20mg Ezanal / 200 Cm2 / 4 hour.
& & If a patient greater than 3 months of age does not meet the minimum weight requirement, the maximum dose of Ezanal cream
& & should be restricted to that which corresponds to patient weight.
* For External Use.
* Store tightly closed at room temp. between 15-30 degrees C, in a cool place.
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