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* Glucovance (metformin – glibenclamide) 500mg/5mg 30 Tablets.
* What is Glucovance used for?
& Glucovance is used to treat patients with type 2 diabetes to help control blood sugar levels.
& It is prescribed in association with diet and exercise to promote better glucose control
& throughout the day.
* When not to take Glucovance?
– Allergy to any of the ingredients, or other sulphonamides,
– Type 1 diabetes (insulin-dependent), severe loss of diabetes control with diabetic ketoacidosis,
& diabetic pre-coma,
– Impaired kidney function,
– Liver insufficiency,
– Severe infection (e.g., bronchopulmonary infection, urinary infection,…),
– Dehydration (e.g., in case of persistent diarrhoea, repeated vomiting,…),
– During the 2 days following radiological studies involving the use of intravascular iodinated contrast
& materials,
– Recent heart attack, heart insufficiency, respiratory insufficiency,
– Excessive consumption of alcoholic beverages,
– Porphyria: accumulation of pigments (porphyrin) in the body,
– In combination with the antifungal agent miconazole,
– Breastfeeding.
* What special precautions should you take whilst taking Glucovance?
# Lactic acidosis:
& Vomiting, abdominal pain accompanied by muscle cramps and/or general malaise with severe fatigue
& occuring during therapy may be signs of severe loss of diabetes control requiring a specific treatment.
& If this occurs, stop taking Glucovance immediately and notify your doctor promptly.
# Hypoglycaemia (abnormally low blood glucose levels):
& During treatment, you may experience hypoglycaemia. Your doctor will explain to you and your family
& members how to recognise the warning signs of hypoglycaemia and how to avoid it, and what to do
& in the case of hypoglycaemia.
& In order to avoid hypoglycaemic episodes:
– Eat balanced meals on a regular basis, including breakfast, because of the increased risk of hypoglycaemia
& if a meal is missed or if your diet contains insufficient or unbalanced levels of sugars,
– The risk of hypoglycaemia is increased by a very severe or poorly balanced diet, by strenuous or prolonged
& exercise, by alcohol intake or by concurrent use of other hypoglycaemic medications,
– Strictly follow the doctor’s prescription.
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