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* Isoptin (Verapamil hydrochloride 80 mg) 30 Tablets.
& & Calcium antagonist for the treatment of coronary insufficiency, cardiac arrhythmias and hypertension.
* Indications:
& & – Chronic coronary insufficiency and long-term treatment of chronic stable and unstable angina –
& & angina at rest including vasospastic angina, angina pectoris after myocardial infarction, Hypertension.
& & – Tacchyarrhymias, such as paroxysmal supraventricular tachycardia, atrial fibrillation/flutter with
& & rapid ventricular response (except in WPW syndrome), premature ventricular beats.
* Dosage and mode of administration:
& & – The dose of Isoptin 80 mg, individualized according to the severity of the disease are to be taken regularly
& & as prescribed by the physician.
& & – The tablets are to be swallowed whole with some liquid, preferably with or shortly after meals.
& & – Unless otherwise instructed, the dose is 1 tablet of Isoptin 80 mg, 3-4 times a day.
& & – On long-term treatment, a daily dose of 480 mg should not be exceeded; short-term dose increases
& & are possible only when directed by the physician.
& & – In patients with impaired hepatic function, depending on the severity of the liver disease, the effect of
& & Verapamil is intensified and prolonged due to diminished drug metabolism. In these cases, dosage should be
& & adjusted with special care.
* Contraindications:
& & – Cardiovascular shock.
& & – Complicated acute myocardial infarction (bradycardia, marked hypotension, left ventricular failure).
& & – Severe conduction disorders (2nd and 3rd degree AV block).
& & – Sick sinus syndrome (bradycardia, tachycardia syndrome).
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