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* PROGEST (Progesterone) 24 S.G. Capsules. For Oral & Vaginal Use. For Menstual Disorders & Endometrial Hyperplasia.
* Composition: Each S.G. Capsule contains:
Progesterone (micronized) 100 mg.
* Indications:
# Oral:
– Treatment of secondary amenorrhea, dysmenorrhea, menorrhagia and other menstrual irregularities due to dysovulation.
– Management of Pre-Menstrual Syndrome (PMS).
– Dysfunctional uterine bleeding.
– Breast pain (post-partum) or benign breast disorders.
– Prevention of estrogen-induced endometrial hyperplasia in menopausal women recieving estrogen Hormone Replacement Therapy (HRT).
# Vaginal: To help pregnancy in cases of:
– Repeated abortion and threatened abortion.
– In vitro fertilization (IVF) cycles.
– Hypofertility or primary or secondary sterility.
– As an alternative to the oral route in case of oral intolerability of the drug.
* Dosage:
# Oral:
– Treatment of progesterone insufficiency (secondary amenorrhea, dysmenorrhea, menorrhagia, dysfunctional uterine bleeding), premenstrual syndrome (PMS), and other menstrual irregularities due to dysovulation: 2-3 capsules (200-300 mg) daily, taken as one capsule (100mg) in the morning and 1-2 capsules (100mg – 200mg) at bedtime for 10 days.
– Prevention of endometrial hyperplasia: 2 capsules (200mg) daily, taken as one capsule (100mg) in the morning and one capsule (100mg) at bedtime or 2 capsules (200mg) daily, taken once at bedtime for 14 days, sequentially with estrogen as Hormone Replacement Therapy (HRT) per 28 day cycle.
# Vaginal:
– To prevent habitual or repeated abortion: one capsule (100mg) on day 13 and 14 of the cycle, then 2 capsules (200mg) in single or 2 divided doses daily from day 15 to day 25 of the cycle. From day 26 of the cycle, and if pregnancy occurs, the dose can be increased to a maximum of 6 capsules (600mg) divided in 3 equal doses daily until day 60, and treatment can be continued till the end of the 12th week of pregnancy (first trimester).
– In threatened abortion: 2-4 capsules (200mg-400mg) daily, in 2 divided doses until the end of the 12th week of pregnancy (first trimester).
– To assist the luteal phase during in vitro fertilization (IVF) cycles: 4-6 capsules (400mg-600mg) daily in 2 or 3 divided doses starting from the day of injection of HCG (Human Chorionic Gonadotrophin) until the end of the 12th week of pregnancy (first trimester).
– To assist the luteal phase in hypofertility or primary or secondary fertility: 2-3 capsules (200mg-300mg) in 2 divided doses, daily for 10 days starting on day 17 of the cycle. When no menstruatiuon occurs, or pregnancy is diagnosed, treatment should be restarted rapidly and continued until the end of the 12th week of pregnancy (first trimester).
* Keep at temperature 15 – 30 degrees C, away from moisture.
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