MEMEXA 10 MG 10 TAB ميميكسا 10 مجم 10 اقراص

Memexa (Memantine hydrochloride) 10 mg 10 film-coated tablets.
* Therapeutic Indications:
& Treatment of patients with moderately severe to severe Alzheimer’s disease.
* Dosage and route of administration:
& Initially, 5 mg (1/2 tablet) daily in the morning for 7 days, then 1 tablet for 7 days
& and then 2 tablets thereafter.
& The dose should be taken either upon arising, or if divided doses upon arising and
& before 2 pm to avoid any problems with agitation in the evening.
* Contraindications:
– Memantine may lower seizure threshold and should be used in patients with a history
& of seizures only with extreme caution.
– Hypersensitivity to the active substance or to any of the other components.
* Precautions and Warnings:
– Concomitant use of N-methyl-D-aspartate (NMDA) antagonists such as amantadine, Ketamine
& or dextromethorphan should be avoided.
– Some factors that may raise urine pH may necessitate careful monitoring of the patient.
& These factors include drastic changes in diet, e.g. from carnivore to vegetarian diet, or
& massive ingestion of alkalizing gastric buffers. Also, Urine pH may be elevated by states
& of renal tubular acidosis (RTA) or severe infections of the urinary tract with Proteus bacteria.
* Pregnancy and Breast-feeding:
– Use in pregnancy should be only if clearly needed.
– Memantine safety in human pregnancy has not been developed and it should only be given
& to pregnant woman only if potential benefit overweighs the potential risk.
– It is not recommended that women taking memantine to breast feed.
* Store in a temperature not exceeding 30 degrees C, in a dry place.