* OVITRELLE® (Choriogonadotropin alfa) 250 micrograms/0.5 ml solution for injection in a pre-filled syringe. 1 pre-filled syringe with 0.5 ml solution for injection. Recombinant human chorionic gonadotropin, trigger final follicular maturation && luteinisation.
** Subcutaneous use. For single use only.
** One pre-filled syringe contains:
250 micrograms (6500 IU) of Choriogonadotropin alfa
** Other ingredients:
Mannitol, methionine, poloxamer 188, diluted phosphoric acid, sodium hydroxide, water for injections.
** Therapeutic indications:
Ovitrelle is indicated in the treatment of:
– Adult women undergoing superovulation prior to assisted reproductive techniques such as in vitro fertilisation (IVF): Ovitrelle is administered to trigger final follicular maturation and luteinisation after stimulation of follicular growth,
– Anovulatory or oligoovulatory adult women: Ovitrelle is administered to trigger ovulation and luteinisation in anovulatory or oligoovulatory women after stimulation of follicular growth.
** Pharmacotherapeutic group:
Sex hormones and modulators of the genital system, gonadotropins, ATC code: G03GA08
** Mechanism of action:
Ovitrelle is a medicinal product of choriogonadotropin alfa produced by recombinant DNA techniques. It shares the amino acid sequence with urinary hCG. Chorionic gonadotropin binds on the ovarian theca (and granulosa) cells to a transmembrane receptor shared with the luteinising hormone, the LH/CG receptor.
** Keep out of the reach and sight of children.
** Store in a refrigerator. Store in the original package. May be stored at or below +25 degrees C for up to 30 days without being refrigerated again during this period and must be discarded if not used during these 30 days.
** Any unused solution or waste material should be disposed of in accordance with local requirements.
** Medicinal product subject to medical prescription.
** Read the package leaflet before use.
** MERCK SERONO
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