# Painful muscle spasms:
– associated with static and functional disorders of the spine (cervical and lumbar syndromes).
– Following surgery, e.g. for herniated intervertebral disc or for osteoarthritis of the hip.
# Spasticity due to neurological disorders e..g multiple sclerosis, chronic myelopathy, degenerative diseases of the spinal cord,
cerebrovascular accidents and cerebral palsy.
– For the relief of painful muscle spasms: 2 to 4 mg three times daily. In severe cases an extra dose of 2 or 4 mg
may be taken at night.
– For spasticity due to neurological disorders: The dosage should be adjusted to the needs of the individual patient.
The initial daily dose should not exceed 6 mg given in 3 divided doses. It may be increased stepwise at half-weekly intervals
by 2 to 4 mg. The optimal therapeutic response is generally achieved with a daily dose between 12 and 24 mg, administered
in 3 or 4 equally spaced doses. The daily dose of 36 mg should not be exceeded.